GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| UVM | cis | rs13008299 | 1 | rs13008299 | chr2:29247997 | FAM179A | chr2:29204164-29275094:+ | -0.68 | -5.22 | 2.78E-6 | Diastolic blood pressure (alcohol consumption interaction) |
| UVM | cis | rs13008299 | 1 | rs13008525 | chr2:29248340 | FAM179A | chr2:29204164-29275094:+ | 0.72 | 5.51 | 9.95E-7 | Diastolic blood pressure (alcohol consumption interaction) |
| UVM | cis | rs13014235 | 1 | rs13014235 | chr2:202215492 | ALS2CR12 | chr2:202153148-202222101:- | -0.46 | -4.69 | 1.82E-5 | Basal cell carcinoma |
| UVM | cis | rs13008299 | 1 | rs13014261 | chr2:29248414 | FAM179A | chr2:29204164-29275094:+ | 0.72 | 5.51 | 9.95E-7 | Diastolic blood pressure (alcohol consumption interaction) |
| UVM | cis | rs13008299 | 1 | rs13026779 | chr2:29247963 | FAM179A | chr2:29204164-29275094:+ | 0.72 | 5.51 | 9.95E-7 | Diastolic blood pressure (alcohol consumption interaction) |
| UVM | cis | rs10935120 | 1 | rs13059720 | chr3:134242021 | ANAPC13 | chr3:134196547-134204865:- | -0.47 | -6.73 | 1.05E-8 | Height |
| UVM | cis | rs9876781 | 1 | rs13069724 | chr3:48478039 | TREX1 | chr3:48501186-48509043:+ | -0.4 | -4.94 | 7.63E-6 | Longevity |
| UVM | cis | rs9876781 | 1 | rs13071337 | chr3:48438189 | TREX1 | chr3:48501186-48509043:+ | -0.38 | -4.81 | 1.22E-5 | Longevity |
| UVM | cis | rs10935120 | 1 | rs13071551 | chr3:134310867 | ANAPC13 | chr3:134196547-134204865:- | -0.45 | -6.73 | 1.03E-8 | Height |
| UVM | cis | rs9876781 | 1 | rs13076076 | chr3:48479039 | TREX1 | chr3:48501186-48509043:+ | -0.4 | -5.1 | 4.38E-6 | Longevity |
| UVM | cis | rs10935120 | 1 | rs13081177 | chr3:134289860 | ANAPC13 | chr3:134196547-134204865:- | -0.46 | -6.57 | 1.88E-8 | Height |
| UVM | cis | rs10935120 | 1 | rs13081688 | chr3:134259954 | ANAPC13 | chr3:134196547-134204865:- | -0.47 | -6.73 | 1.05E-8 | Height |
| UVM | cis | rs10935120 | 1 | rs13087875 | chr3:134261123 | ANAPC13 | chr3:134196547-134204865:- | -0.46 | -6.87 | 6.1E-9 | Height |
| UVM | cis | rs10935120 | 1 | rs13089966 | chr3:134279197 | ANAPC13 | chr3:134196547-134204865:- | -0.45 | -6.73 | 1.03E-8 | Height |
| UVM | cis | rs10935120 | 1 | rs13090969 | chr3:134307257 | ANAPC13 | chr3:134196547-134204865:- | -0.45 | -6.73 | 1.03E-8 | Height |